Jean Aranguren hit the go-ahead layup with 2:19 left Wednesday night for Hofstra, which produced a defensive stand in the final seconds to upset Seton Hall 49-48 in Uniondale, N.Y.Aranguren had 13 points and Seton Hall transfer Jaquan Sanders added 12 points for Hofstra (3-0).Chaunce Jenkins had 18 points and Dylan Addae-Wusu finished with 11 points for Seton Hall, which has lost two straight and is 1-2 for the first time since 2020-21.Seton Hall led 24-22 following a sludgy first half in which the teams shot a combined 31.5 percent (17-for-54), including 25.9 percent (7-for-27) from 3-point land.Sanders hit a driving layup and Cruz Davis dunked following a steal at midcourt to put Hofstra up 40-39 with 5:12 left. Sanders’ basket was preceded by a nine-second stretch in which the Pirates missed 5 of 6 free throws.Seton Hall’s Prince Aligbe and Aranguren traded layups before the teams turned the ball over on consecutive possessions.